Endocrine Abstracts

Background: Polycystic ovary syndrome is the most common endocrinopathy among females in reproductive ages. PCOS is not accepted only a reproductive pathology but also accepted as a metabolic problem. Prolonged QTc interval showing ventricular repolarization is a major risk factor for the arrhythmias, coronary heart diseases, and sudden cardiac death. Although hyperinsulinism and hyperandrogenism is known as common manifestations of PCOS, there is conflicting data a...

A 21-year-old female (height: 148 cm, weight: 38 kg, and BMI: 17) was referred to our endocrinology outpatient polyclinic with the complaints of severe abdominal pain and severe hypertriglyceridemia. The patient’s medical history revealed diabetes and FMF. Physical examination revealed a marked loss of subcutaneous fat from the extremities leading to prominence of muscular contours and veins, with excess fat around the face, submental and dorsocervical region. Despite the...

Introduction: Carbohydrate antigen 19-9 (CA 19-9) is a glycosphingolipid of the Lewis blood group that for years has been proposed as a useful marker for epithelial type gastrointestinal cancers. It is well known that moderately increased concentrations of CA 19-9 can be found in 15–36% of patients with benign conditions such as pancreatic, liver, biliary diseases and benign hydronephrosis. In current study, we aimed to investigate whether there was any tendency CA 19-9 e...

Pituitary apoplexy (PA) is an endocrine emergency characterized by acute, severe headache, visual disturbances, ophthalmoplegia, hypopituitarism and altered consciousness. This condition usually arises in an underlying pituitary adenoma. 27-year-old female without a known pitutary lesion presented to the emergency department in December 2015 with a 8-hour history of with sudden and severe frontal headache, fever, blurred vision, nausea, confusion at 36 weeks of gestation. The ...

Introduction: Although dipeptidyl peptidase-4 (DPP-4) inhibitores are generally safe and are associated with less side effects compared to other oral antidiabetic medications, they could also be associated with some side effects including skin rash. Herein we report the first case of a type 2 diabetes patient who developed a painfull maculopapular rash induced by linagliptin, a widely used DPP-4 inhibitor.Case presentation: A-54-year old female patient w...